The reference site for Brompheniramine

Brompheniramine (Bromfed, Dimetapp, Bromfenex, Dimetane, BPN, Lodrane), commonly marketed as its salt brompheniramine maleate, is an antihistamine drug of the propylamine (alkylamine) class.

WHAT IS Brompheniramine?

Brompheniramine is an antihistamine of the propylamine class. It works by blocking the effects of the naturally occurring chemical histamine in the body.
It is commonly available over the counter and is indicated for the treatment of the symptoms of the common cold and allergic rhinitis, such as runny nose, itchy and watery eyes, and sneezing. It also may relieve the itching of insect bites, bee stings, poison ivy, and poison oak.
Brompheniramine is more commonly known by its brand names Bromfed®, Bromfenex®, and Dimetane®, amongst others.


Brand Name(s): Bromarest; Bromfed; BroveX;
Dimetane; Lodrane 12 Hour; Rondec; Veltane

CAS nº: 86-22-6

(brome feh neer a meen)


Product Info

The sections below will provide you with more specific information and guidelines related to Brompheniramine and its correct use. Please read them carefully.

FDA Information

Brompheniramine has been approved by the Food and Drug Administration in 1956.

Please visit the official site of the FDA for further information.

Why is this medication prescribed?

Brompheniramine is an antihistamine drug of the propylamine class.

This medicine is commonly available over the counter and is indicated for the treatment of the symptoms of the common cold and allergic rhinitis, such as runny nose, itchy and watery eyes, and sneezing. It also may relieve the itching of insect bites, bee stings, poison ivy, and poison oak.

Antihistamines mechanism:

Human cells have three different types of histamine receptors (H1, H2, and H3). Histamine works by attaching itself to these receptors on the surface of cells and thereby causing its effects. It is mainly through the H1 receptors that histamine causes symptoms of allergy. Antihistamines act by attaching to these same H1 receptor sites, thereby preventing histamine from binding to them. This action prevents the histamine from causing allergic symptoms.

Histamines can cause swelling, sneezing, itching (nose, throat, roof of mouth), and a runny nose through the nostrils or down the back of the throat (post-nasal drip). Antihistamines are effective in treating the sneezing, running, and itching. They usually begin working between 30 to 60 minutes after being taken.

However, histamine is only one of the many chemicals involved in the allergic reaction, which explains why relief from antihistamines is usually only partial.

Other uses for this medicine

This medication has not been approved for any alternative uses other than those mentioned in the product information section.

Dosage and using this medicine

Brompheniramine comes as a regular tablet, extended-release (long-acting) tablet, and syrup.

It is important to take this medicine exactly as indicated on the package or as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

This medicine can be taken with or without food, and with a full glass of water.

Do not crush, chew, or break the extended or timed-release forms of brompheniramine. Swallow them whole. They are specially formulated to release the medication slowly in the body.

Furthermore, to ensure that you get a correct dose, measure the liquid form of brompheniramine with a special dose-measuring spoon or cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.

Additionally, do not take more of this medication than is prescribed or is recommended on the package. The maximum amount of brompheniramine that you should take in 1 day is 24 mg. The regular release tablets and the syrup are usually taken every 4 to 6 hours as needed (four to six times a day). The sustained release tablets and capsules are usually taken every 8 to 12 hours as needed (two or three times a day).

If your symptoms do not improve, or if they worsen, contact your healthcare provider.

What special precautions should I follow?


Tell your doctor if you have glaucoma or increased pressure in the eye, a stomach ulcer, an enlarged prostate, bladder problems or difficulty urinating, an overactive thyroid (hyperthyroidism), asthma, hypertension or any type of heart problems. Moreover, do not take brompheniramine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan®), phenelzine (Nardil®), or tranylcypromine (Parnate®) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

You may not be able to take brompheniramine, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

Brompheniramine is in the FDA pregnancy category C. This means that it is not known whether brompheniramine will be harmful to an unborn baby. Do not take brompheniramine without first talking to your doctor if you are pregnant or could become pregnant during treatment.

Additionally, this medicine passes into breast milk. Infants are especially sensitive to the effects of antihistamines, and serious side effects could occur in a nursing infant. Do not take brompheniramine without first talking to your doctor if you are nursing a baby.

If you are over 60 years of age, you may be more likely to experience side effects from brompheniramine. You may require a lower dose of this medication.

Use cautiously when driving, operating machinery, or performing other hazardous activities. Brompheniramine may cause dizziness or drowsiness. So too, alcohol may increase these symptoms and should be taken in moderation.

What should I do if I forget a dose?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose.

Do not take a double dose of this medication unless otherwise directed by your doctor.

What side effects can this medication cause?

Stop taking brompheniramine and seek emergency medical attention if you experience a rare but serious allergic reaction (for example, difficulty breathing, closing of the throat, swelling of the lips, tongue, or face, or hives).

Other less serious side effects may be more likely to occur. Continue to take brompheniramine and talk to your doctor if you experience:

sleepiness, fatigue, or dizziness
difficulty urinating or an enlarged prostate
dry mouth

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What storage conditions are needed for this medicine?

Always keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Also, throw away any medication that is outdated or no longer needed and, if required, talk with your pharmacist about the proper disposal of your medication.

In case of an emergency/overdose

In the case of an overdose, call your local poison control center at 1-800-222-1222. However, if the victim has collapsed or is not breathing, call the local emergency services on 911.

Symptoms of overdose may include:

extreme sleepiness
ringing in the ears
blurred vision
large pupils
dry mouth


Product Images


Below you will find images and specific information on the principal types of brompheniramine that exist, including their respective brand name(s), strength, inscription codes, manufacturers and/or distributors.
The information below includes general information and guidelines for patients taking this medication and should never be used to substitute professional medical advice that can be provided by a qualified physician or family doctor.

Strength(s): 6 MG
Imprint: ECR 6


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